Endocrine Abstracts

Background: Adults with untreated GH deficiency (GHD) may have a cluster of cardiovascular risk factors. The effects of GH replacement therapy on insulin homeostasis in GHD subjects are still debated. Only a few studies investigated the effects of GHD and GH therapy on glucose metabolism in children.Objective: To evaluate the effects of GHD and GH treatment on glucose metabolism in a large cohort of GHD children before and after GH replacement therapy.</...

Background: Craniopharyngiomas are benign tumors of the parasellar and sellar region. Patients with craniopharyngioma, treated with surgery, have comorbidities such as obesity and multiple pituitary deficiencies.Aim: To evaluate the metabolic parameters of patients with craniopharyngioma treated with surgery.Methods: We recruited 20 patients with craniopharyngioma (M=11, 46.6±12.6) and 20 patients (M=10, 53.5&#17...

Introduction: Italy is considered a country with high prevalence of 25 OH vitamin D deficiency. Changes in vitamin D serum levels were linked with the onset and progression of several diseases, including osteoporosis and cardiovascular diseases. The hypopituitary patients show several comorbidities like cardiovascular diseases and osteoporosis.Purpose: To evaluate the prevalence of vitamin D deficiency in hypopituitary patients.Pat...